On the Mechanisms of Calcification.

Publisher Website
Google Scholar
Abstract
Specimens of skin, tendon, and cortical bone from the calf were exhaustively demineralized with ethylene diamine tetraacetic acid at pH 7.4. These tissues were then equilibrated with solutions of varying Ca and P content. All 3 tissues, presumably because of their collagen content, were able to induce formation of hydroxy apatite crystals from otherwise stable solutions. In contrast to skin and tendon, bone removed Ca from all solutions, but all 3 tissues were equally efficient in crystal seeding.

This publication has 5 references indexed in Scilit: