Cytotoxicity: Specificity after in vitro Sensitization
- 25 December 1970
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 170 (3965) , 1406-1409
- https://doi.org/10.1126/science.170.3965.1406
Abstract
Animals sensitized in vivo against an allogeneic tissue subsequently show accelerated rejection specificially of that or antigenically similar tissues. Lymphocytes sensitized in vitro will destroy target cells isogeneic with the sensitizing cells. Lymphocytes sensitized in vitro can differentiate specifically between different allogeneic target cells—as occurs in vivo.Keywords
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