RADIOTHERAPY OF BRAIN METASTASES - CONVENTIONAL VERSUS CONCENTRATED TREATMENT

  • 1 January 1982
    • journal article
    • research article
    • Vol. 158  (1) , 20-22
Abstract
From Jan. 1975-March 1981, 97 consecutive patients with brain metastases from various tumors were treated with Co radiotherapy. Two successive treatment schedules were employed. The 1st 52 patients were treated according to a conventional schedule (30 or 40 Gy [gray] in 15 or 20 treatments over a 3 or 4 wk period); in the successive 45 patients a concentrated schedule was employed (2 series of 17 Gy in 2 sessions over a 3 day period, separated by an interval of 3 wk). In the 87 evaluable patients, no significant difference was noted regarding the efficacy of radiotherapeutic treatment (25/47 and 20/40 partial remissions, respectively, with median survival of 4 and 3 mo., respectively). Acute toxicity was more relevant with concentrated irradiation (.apprx. 20% of cases).

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