Adult-Onset Nemaline Rods in a Patient Treated for Suspected Dermatomyositis
- 1 December 1981
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 38 (12) , 761-766
- https://doi.org/10.1001/archneur.1981.00510120061010
Abstract
• A 65-year-old woman with progressive muscle weakness and a diffuse rash of three years' duration was examined. Muscle tissue was studied with histochemical techniques, phase-contrast microscopy, electron microscopy, and twodimensional electrophoresis. Histochemical studies showed numerous nemaline rods, with a normal ratio of types I and II fibers. Two-dimensional electrophoresis revealed abnormalities in the myosin light chain and tropomyosin protein patterns when compared with normal and diseased muscle biopsy samples, including those from two patients with adult-onset dermatomyositis.This publication has 5 references indexed in Scilit:
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