Lowering Cholesterol with Drugs and Diet

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Abstract
Expert panels in the United States and Europe have reinforced guidelines on lowering cholesterol as one of the fundamental preventive measures to reduce mortality from coronary heart disease.1,2 Last year the report of the Scandinavian Simvastatin Survival Study strengthened the evidence on which the guidelines were based, demonstrating a survival benefit from lowering cholesterol with simvastatin in patients with coronary disease.3 One remaining question has been whether aggressive cholesterol lowering in persons without overt coronary heart disease will result in similar benefits, without increasing the risk of noncardiac mortality. Another problem has been to find effective methods for lowering . . .