Measurement of right and left ventricular volumes in healthy individuals with cine MR imaging.

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Abstract
Cine magnetic resonance (MR) imaging is a new, rapid MR pulse sequence that acquires up to 32 images per cardiac cycle at up to four levels of the heart within 4 minutes. In this study, the whole heart was encompassed by contiguous 10-mm transverse sections. Ventricular volumes were calculated by adding luminal areas determined in each section at end-diastole and end-systole. The left ventricular volume index was 57 ml/m2 .+-. 9 at end-diastole and 17 ml/m2 .+-. 4 at end-systole. The right ventricular volume index was 63 ml/m2 .+-. 9 at end-diastole and 22 ml/m2 .+-. 6 at end-systole. The left to right ventricular stroke volume ratio was 0.97 .+-. 0.06, which was not statistically different from the theoretically expected ratio of 1. Interobserver and intraobserver measurements were closely correlated. Volume measurements were validated with two-dimensional echocardiography in five volunteers. Cine MR imaging allows reproducible three-dimensional measurement of right and left ventricular volumes with short imaging time and good temporal resolution.