The fine structure of stratified ependyma in the ventricular wall of N-ethyl-N-nitrosourea-treated rats
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Acta Neuropathologica
- Vol. 46 (3) , 173-176
- https://doi.org/10.1007/bf00690840
Abstract
Summary Ependymal stratifications, up to 15 cell layers in thickness at the floor of the lateral ventricle of rats treated transplacentally with N-ethyl-N-nitrosourea (ENU), are described. Ultrastructurally the constitutent ependymal cells are well-differentiated and show no morphological signs of neoplasia. The possibility that these findings are due to the toxicity or carcinogenicity of ENU is discussed.Keywords
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