Abstract
Improved syntheses for DL-u-amino-β-(3-hydroxy-4-oxo-1,4-dihydro-l-pyridyl)propionic acid (DL- mimosine) and related 3-hydroxy-4(1H)-pyridones are described. The condensation of α, β -diamino- propionic acid with 4-pyrones involves preferential reaction at the β-amino group at pH > 12, obviating the necessity to mask the α-amino function during the syntheses.

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