Abstract
Cyclocondensation reaction of 3-isatylideneoxime (1a), -hydrazone (1b), -phenyl-hydrazone (1c), semicarbazone (1d) and -thiosemicarbazone (1e) with chloroacetyl chloride (and thioglycolic acid) gave the corresponding spiro azetidinones (2) and spiro thiazolidinones (3). 3-Isatylidenehydrazone (1b) was condensed easily with aromatic aldehydes afforded a new 3-isatylidene azomethines (4) which submitted for cyclocondensation reaction with chloroacetyl chloride (and thioglycolic acid) giving bis-azetidinones (5) and bis-thiazolidinones (6), respectively.

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