Asymmetric substituent effect on the reaction of (R)- and (S)-indan-1-carboxylic acids with (S)-α-phenylethylamine derivatives
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 19,p. 830
- https://doi.org/10.1039/c39780000830
Abstract
In the reaction of (R)- and (S)-indan-1-carboxylic acids with (S)-α-phenylethylamines, the substituent effect is highly stereoselective and the equilibrium constants KSS and KRS are affected by inductive and resonance effects of the substituent at the para position of phenylethylamine rather than by steric hindrance.Keywords
This publication has 0 references indexed in Scilit: