Synthesis of dipyrazolo[3,4-b : 4′,3′-f]azepines and dithieno[2,3-b : 3′,2′f]azepines from 1-substituted 2,7-dichloro-4,5-dihydro-1H-azepine-3,6-dicarbaldehydes
- 1 January 1989
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 11,p. 2095-2098
- https://doi.org/10.1039/p19890002095
Abstract
Syntheses of the title compounds (7) and (8) are described. These new bis-heterocyclic analogues of dibenzo[b,f]azepines (4) were readily obtained from the di-β-chlorovinyl aldehydes (3), the latter prepared by formylation of the azepines (5). The thiophene analogue (10) of the antidepressant ‘imipramine’ was then synthesized by debenzylation of the dithienoazepine (8a) followed by condensation with an appropriate halide.Keywords
This publication has 0 references indexed in Scilit: