Effects of bicuculline and chlordiazepoxide on locomotor activity and avoidance performance in rats
- 1 October 1980
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 36 (10) , 1208-1210
- https://doi.org/10.1007/bf01976133
Abstract
Bicuculline, at a dose of 1 mg/kg which, per se, failed to change locomotor activity in rats, counteracts the facilitating effect induced by chlordiazepoxide (10 mg/kg). Conversely, bicuculline (1 mg/kg) does not modify the decrease of motor activity and the disruption of avoidance performance induced by this benzodiazepine derivative (20 mg/kg).This publication has 12 references indexed in Scilit:
- Comparative study of the antagonism of bemegride and picrotoxin on behavioural depressant effects of diazepam in rats and miceNeuropharmacology, 1978
- Facilitating effects of chlordiazepoxide on locomotor activity and avoidance behaviour of reserpinized micePsychopharmacology, 1978
- FURTHER EVIDENCE FOR GABA-ERGIC MECHANISMS IN ACTION OF BENZODIAZEPINES1977
- Antagonism of diazepam against central anticholinergic drug-induced hyperactivity in mice: Involvement of a GABA mechanismNeuropharmacology, 1976
- Effects of chlordiazepoxide, CNS stimulants and their combinations on avoidance behaviour in mice.1975
- Effects of P-chlorophenylalanine (PCPA) on avoidance conditioning in guinea pigsPharmacological Research Communications, 1974
- Genotype-dependent sensitivity and tolerance to morphine and heroin: Dissociation between opiate-induced running and analgesia in the mousePsychopharmacology, 1974
- A comparison of the effects of some benzodiazepines and other drugs on aggressive and exploratory behaviour in mice and ratsNeuropharmacology, 1970
- EFFECTS OF CENTRALLY ACTING DRUGS ON EXPLORATORY BEHAVIOUR IN RATSBritish Journal of Pharmacology and Chemotherapy, 1965
- Drug-induced modifications of discriminated avoidance behavior in ratsPsychopharmacology, 1965