A 65-Kilobase Pathogenicity Island Is Unique to Philadelphia-1 Strains of Legionella pneumophila
Open Access
- 1 August 2003
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 185 (15) , 4630-4637
- https://doi.org/10.1128/jb.185.15.4630-4637.2003
Abstract
Nucleotide sequence analysis of an ∼80-kb genomic region revealed an ∼65-kb locus that bears hallmarks of a pathogenicity island. This locus includes homologues of a type IV secretion system, mobile genetic elements, and known virulence factors. Comparative studies with other Legionella pneumophila strains and serogroups indicated that this ∼65-kb locus is unique to L . pneumophila serogroup 1 Philadelphia-1 strains.Keywords
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