THERAPEUTIC RESULTS WITH CONCENTRATED SCARLET FEVER ANTITOXIN

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Abstract
About one year ago, we1reported a scarlet fever antitoxin produced by immunizing horses with scarlet fever toxin. The antitoxic serum thus obtained was concentrated by the method commonly employed for the concentration of diphtheria antitoxin. Up to that time, the serums prepared for the treatment of scarlet fever had been produced by immunizing horses with living cultures of hemolytic streptococci. Since Moser2reported his serum, in 1902, many antistreptococcic serums have been prepared, but there has been no reason to believe that any of them are more efficient than the serum described twenty-three years ago. Moser reported a large series of scarlet fever cases treated with his serum, and two control series: one treated with Marmorek's serum, the other with normal horse serum. There is no doubt that Moser's serum exerted a favorable influence on the temperature, rash and general condition in many cases of scarlet fever.

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