N‐Terminal sequence similarities between components of the multicatalytic proteinase complex
- 26 March 1990
- journal article
- Published by Wiley in FEBS Letters
- Vol. 262 (2) , 327-329
- https://doi.org/10.1016/0014-5793(90)80220-d
Abstract
The multicatalytic proteinase complex is a high molecular weight nonlysosomal proteinase which is composed of many different types of subunit. As part of a study of the possible relationships between subunits, polypeptides derived from the multicatalytic proteinase from rat liver have been subjected to N-tenninal amino acid sequence analysis. Although several of the subunits are blocked at their N-termini, sequences have been obtained for 7 of the polypeptides. Each of the 7 sequences is unique but they show considerable sequence similarity, suggesting that the proteins are encoded by members of the same gene family.Keywords
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