Lymphocyte transformation test in allergic contact nickel dermatitis
- 29 July 2006
- journal article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 92 (1) , 9-15
- https://doi.org/10.1111/j.1365-2133.1975.tb03027.x
Abstract
Twenty-five patients with clinically proven, patch test positive nickel dermatitis were studied with the lymphocyte transformation test (LTT). Serial dilutions of NiSO4 were present in the lymphocyte culture. None of the controls showed lymphocyte blast transformation. In fourteen patients maximal incorporation of thymidine occurred at the highest dilutions (I:50,000-I:100,000). In eleven patients the highest incorporation occurred at the lower dilutions. The nature of the antigen responsible for the specific reaction remains unknown.Keywords
This publication has 4 references indexed in Scilit:
- NICKEL ANTIBODIES*British Journal of Dermatology, 1972
- The Specificity of Lymphocyte Transformation In Vitro By Nickel Salts in Nickel Sensitive SubjectsJournal of Investigative Dermatology, 1972
- Non-Specific Lymphocyte Transformation In Vitro By Nickel Acetate**From the Departments of Internal Medicine an Dermatology, University of Cologne. Cologne, West Germany. Reprint requests to: Priv. Doz. Dr. C. E. Orfanos, Dermatological Clinic of the University of Cologne, 5, Köln-Lindenthal, West Germany.Journal of Investigative Dermatology, 1970
- THE UPTAKE OF LABELLED THYMIDINE BY LEUCOCYTES OF NICKEL SENSITIVE PATIENTSBritish Journal of Dermatology, 1970