Influence of CO2 on Respiratory Metabolism of Ehrlich Ascites Tumor.
- 1 July 1960
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 104 (3) , 446-448
- https://doi.org/10.3181/00379727-104-25869
Abstract
The effect of CO2 on respiratory metabolism of Ehrlich ascites tumor cells was studied with the Cartesian diver technic. In absence of substrate and in presence of glucose, pyruvate or oxalacetate, CO2 had a pronounced inhibitory effect upon respiration. Only butyrate addition was found to neutralize CO2 inhibition. The stimulatory effect upon respiration shown for pyruvate, oxalacetate and glucose (at a 1 mM concentration) in a CO2 free atmosphere, could, when CO2 was present in the gas phase, be demonstrated only for glucose.Keywords
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