STIMULATION OF MICROSOMAL NADPH OXIDATION BY QUINONE GROUP-CONTAINING ANTICANCER CHEMICALS
- 1 January 1976
- journal article
- research article
- Vol. 67 (4) , 523-528
Abstract
Mitomycin C, carbazilquinone, daunomycin and adriamycin stimulated the [rat liver] microsomal NADPH oxidase system by acting as an electron carrier from NADPH cytochrome c reductase to O2. The former 2 enhanced O2 uptake of Ehrlich [mouse] ascites cells in the presence of glucose, but the latter 2 did not.This publication has 2 references indexed in Scilit:
- Hepatic Triphosphopyridine Nucleotide-Cytochrome c Reductase: Isolation, Characterization, and Kinetic StudiesJournal of Biological Chemistry, 1962
- Specificity of the stimulation by quinones of direct oxidation of glucose by brain slicesBiochimica et Biophysica Acta, 1962