ACTH, LPH and β-Endorphin Secretion from Perfused Isolated Human Pituitary Tumour Cells in vitro
- 1 January 1980
- journal article
- Published by S. Karger AG in Hormone Research
- Vol. 13 (4-5) , 280-290
- https://doi.org/10.1159/000179295
Abstract
We report the chromatographic characterization of the ACTH- and LPH-related peptides released from isolated cells prepared from human ACTH-secreting pituitary tumours obtained at surgery (trans-sphenoidal hypophysectomy) from 2 patients with pituitary-dependent Cushing's disease and 2 patients with Nelson's syndrome. The dynamic release of these peptides in response to various stimuli, including rat stalk-median eminence extract (SME) and synthetic arginine vasopressin (AVP) was studiedKeywords
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