Effect of·OH Scavengers on Radiation Damage to the Erythrocyte Membrane
- 1 January 1982
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 41 (5) , 473-481
- https://doi.org/10.1080/09553008214550551
Abstract
Thiourea, an ·OH scavenger, reduced the gamma-radiation-induced changes in the rigidity of erythrocyte membrane lipids, the state of membrane proteins, and lipid peroxidation. Several ·OH scavengers, but not superoxide dismutase, also inhibited the radiation-induced acceleration of the transport of a hydrophilic non-electrolyte spin label TEMPOL across the erythrocyte membrane. The effects of scavengers were usually biphasic with a maximum of the protective effect. Higher concentrations of the scavengers were less effective, as in the case of radioprotection of erythrocytes to haemolysis studied previously.This publication has 27 references indexed in Scilit:
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