Acute Hyperkalemia Risks in Recipients of Kidney Graft Cooled with Collins’ Solution

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Abstract
The 1st case of cardiac arrest [in humans], occurring at the time of vessel clamps removal, of a kidney transplantation cooled prior to grafting with Collins'' solution is presented. Monitoring of cardiac K has demonstrated the role of Collins'' solution (K = 141 meq/l) in the genesis of this incident. The mean .+-. SD increase of the K concentration in the right atrium within the seconds following the removal of the graft vessels clamps was 2.6 .+-. 1.5 meq. Acute electrocardiographic abnormalities primarily represented by sudden apparition of hyperkalemic T waves and extrasystols occur in more than 50% of the cases. The effects of progressive blood release in the graft and other preventive manipulations were studied and discussed.

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