Asymmetric Synthesis of Ring Functionalizedtrans-2,6-Disubstituted Piperidines fromN-Sulfinyl δ-Amino β-Keto Phosphonates. Total Synthesis of (−)-Myrtine
- 17 February 2007
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 72 (6) , 2046-2052
- https://doi.org/10.1021/jo062365t
Abstract
Sulfinimine-derived N-sulfinyl δ-amino β-ketophosphonates are transformed via the enaminones to the phosphoryl dihydropyridones that selectively give trans-2,6-disubstituted 1,2,5,6-tetrahydropyridines on organocuprate addition and dephosphorylation.Keywords
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