Safety and Efficacy of a Lentiviral Vector Containing Three Anti-HIV Genes—CCR5 Ribozyme, Tat-rev siRNA, and TAR Decoy—in SCID-hu Mouse–Derived T Cells
Open Access
- 1 June 2007
- journal article
- Published by Elsevier in Molecular Therapy
- Vol. 15 (6) , 1182-1188
- https://doi.org/10.1038/sj.mt.6300157
Abstract
No abstract availableKeywords
This publication has 48 references indexed in Scilit:
- Ex Vivo Selection and Expansion of Cells Based on Expression of a Mutated Inosine Monophosphate Dehydrogenase 2 after HIV Vector Transduction: Effects on Lymphocytes, Monocytes, and CD34+ Stem CellsMolecular Therapy, 2006
- T-cell protection and enrichment through lentiviral CCR5 intrabody gene deliveryGene Therapy, 2006
- Gene-Based Immunotherapy for Human Immunodeficiency Virus Infection and Acquired Immunodeficiency SyndromeHuman Gene Therapy, 2006
- Off-target effects by siRNA can induce toxic phenotypeRNA, 2006
- Long-Term Inhibition of HIV-1 Infection in Primary Hematopoietic Cells by Lentiviral Vector Delivery of a Triple Combination of Anti-HIV shRNA, Anti-CCR5 Ribozyme, and a Nucleolar-Localizing TAR DecoyMolecular Therapy, 2005
- Current status of gene therapy strategies to treat HIV/AIDSMolecular Therapy, 2005
- Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral loadMolecular Therapy, 2004
- Downregulation of the CCR5 β-Chemokine Receptor and Inhibition of HIV-1 Infection by Stable VA1-Ribozyme Chimeric TranscriptsAntisense and Nucleic Acid Drug Development, 2000
- CHEMOKINE RECEPTORS AS HIV-1 CORECEPTORS: Roles in Viral Entry, Tropism, and DiseaseAnnual Review of Immunology, 1999
- In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral VectorScience, 1996