FETAL ERYTHROPOIESIS IN STEEL MUTANT MICE .3. DEFECT IN DIFFERENTIATION FROM BFU-E TO CFU-E DURING EARLY DEVELOPMENT
- 1 January 1978
- journal article
- research article
- Vol. 51 (3) , 539-547
Abstract
Erythroid progenitor [mouse] cells in +/+ and Sl/Sld fetal livers manifested as erythroid burst-forming units (BFU-E) and erythroid colony-forming units (CFU-E) were assayed in vitro during early development. The proportion of BFU-E was higher in mutant than in normal fetal livers. The proportion of CFU-E was less in the mutant than in the normal. The defect in Sl/Sld fetal hepatic erythropoiesis is apparently expressed at the steps of differentiation that effect the transition from BFU-E to CFU-E.This publication has 5 references indexed in Scilit:
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