Zinc in Wound Healing
- 26 September 1974
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 291 (13) , 675-676
- https://doi.org/10.1056/nejm197409262911311
Abstract
Zinc plays an important part in protein synthesis. It is essential for the normal activity of DNA polymerase,1 and is present in RNA polymerase.2 It also appears to be an obligatory participant in the synthesis of collagen.3 Its removal from DNA polymerase inhibits the polymerase activity, whereas complete activity is restored after incubation with zinc ions.1 On a physiologic level, zinc is crucial for growth and development. It is an essential nutrient for higher plants.4 Micro-organisms require zinc for the synthesis of several essential enzymes and proteins.5 Animals fed zinc-deficient diets have anorexia, hypogeusia, growth retardation and various skin dystrophies, . . .Keywords
This publication has 7 references indexed in Scilit:
- Escherichia coli Deoxyribonucleic Acid Polymerase I, a Zinc MetalloenzymeJournal of Biological Chemistry, 1973
- Influence of zinc deficiency on synthesis and cross-linking of rat skin collagenBiochimica et Biophysica Acta (BBA) - General Subjects, 1973
- SERUM-ZINC AND HEALING OF VENOUS LEG ULCERSThe Lancet, 1972
- Plasma zinc as an indicator of zinc status in ratsBritish Journal of Nutrition, 1972
- The Presence and Possible Role of Zinc in RNA Polymerase Obtained from Escherichia coliProceedings of the National Academy of Sciences, 1971
- ACCELERATION OF WOUND HEALING IN MAN WITH ZINC SULPHATE GIVEN BY MOUTHThe Lancet, 1967
- EVIDENCE ON THE INDISPENSABLE NATURE OF ZINC AND BORON FOR HIGHER GREEN PLANTSPlant Physiology, 1926