pH-Dependent Inactivation and Reactivation of Recombinant Sheep Angiotensinogen

Abstract
Purified recombinant sheep angiotensinogen (rsAngn) lost 74% of the reactivity with human renin during storage at pH 8.0 and 4°C. The inactivated rsAngn was reactivated by incubation at acidic pHs. This indicates that pH-dependent inactivation and reactivation occur in rsAngn.

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