Effects of the Prevention of Coprophagy in the Rat
- 1 May 1959
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 68 (1) , 121-130
- https://doi.org/10.1093/jn/68.1.121
Abstract
Essential fatty acid deficiency in the rat is hastened by complete prevention of coprophagy. This observation does not imply that these fatty acids are synthesized in the large intestine, but does show that the unsaturated fatty acids of the feces are, in part at least, of an essential nature. The serum cholesterol of the essential fatty acid-deficient rat is lower than is obtained by merely feeding a fat-free diet without the development of the deficiency syndrome. Furthermore, it appears that the level of serum cholesterol in the deficient rat may not respond to dietary changes such as the inclusion of saturated fat in the same manner that is observed in the non-deficient animal. Accumulation of liver cholesterol in the non-deficient as well as the deficient rat receiving a fat-free diet has been confirmed.Keywords
This publication has 11 references indexed in Scilit:
- A NEW DEFICIENCY DISEASE PRODUCED BY THE RIGID EXCLUSION OF FAT FROM THE DIETPublished by Elsevier ,2021
- The effect of the nature of dietary fat on synthesis of cholesterol from acetate-1-C14 in rat liver slicesArchives of Biochemistry and Biophysics, 1958
- Prevention of Coprophagy in the RatJournal of Nutrition, 1957
- The Effect of Fat Level of the Diet on General Nutrition XIV. Further Studies of the Effect of Hydrogenated Coconut Oil on Essential Fatty Acid Deficiency in the RatJournal of Nutrition, 1955
- Fat Excretion The Influence of Dietary Fat on Fecal Fat ExcretionJournal of Nutrition, 1954
- The effect of essential fatty acid deficiency on the distribution of endogenous cholesterol in the plasma and liver of the ratArchives of Biochemistry and Biophysics, 1954
- A New Salt Mixture for Use in Experimental DietsJournal of Nutrition, 1937
- The effect of various fats in the production of dietary fatty liversBiochemical Journal, 1936
- VITAL NEED OF THE BODY FOR CERTAIN UNSATURATED FATTY ACIDSPublished by Elsevier ,1932
- Some Observations on the Growth of Rats on "Fat-Free" and Fat-Containing Diets.Experimental Biology and Medicine, 1930