Primary structure of the α‐subunit of bovine adenylate cyclase‐stimulating G‐protein deduced from the cDNA sequence
Open Access
- 20 January 1986
- journal article
- Published by Wiley in FEBS Letters
- Vol. 195 (1-2) , 220-224
- https://doi.org/10.1016/0014-5793(86)80164-8
Abstract
The primary structure of the α‐subunit of the adenylate cyclase‐stimulating G‐protein (Gs) has been deduced from the nucleotide sequence of cloned DNA complementary to the bovine cerebral mRNA encoding the polypeptide. Comparison of the amino acid sequences of the α‐subunits of Gs and transducin reveals that some of the highly conserved regions show sequence homology with elongation factor‐Tu and ras p21 proteins and correspond to functional regions of guanine nucleotide‐binding proteins.Keywords
This publication has 32 references indexed in Scilit:
- A Model for the Tertiary Structure of p21, the Product of the ras OncogeneScience, 1985
- Molecular Cloning of Complementary DNA for the Alpha Subunit of the G Protein that Stimulates Adenylate CyclaseScience, 1985
- Primary structure of the α-subunit of transducin and its relationship to ras proteinsNature, 1985
- Sequence of the Alpha Subunit of Photoreceptor G Protein: Homologies Between Transducin, ras , and Elongation FactorsScience, 1985
- Homologies Between Signal Transducing G Proteins and ras Gene ProductsScience, 1984
- A simple method for displaying the hydropathic character of a proteinJournal of Molecular Biology, 1982
- The structure of eight distinct cloned human leukocyte interferon cDNAsNature, 1981
- Isolation of biologically active ribonucleic acid from sources enriched in ribonucleaseBiochemistry, 1979
- Empirical Predictions of Protein ConformationAnnual Review of Biochemistry, 1978
- 3′ Non-coding region sequences in eukaryotic messenger RNANature, 1976