The effect of cholinergic antagonists on a central response to nicotine
- 1 January 1982
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 38 (1) , 119-120
- https://doi.org/10.1007/bf01944563
Abstract
Mecamylamine and hexamethonium antagonize the prostration response of rats to centrally-administered nicotine; decamethonium and d-tubocurarine are less effective. Physostigmine does not elicit the response. Nicotine's central cholinergic effect thus may contribute to but does not fully account for its action.This publication has 6 references indexed in Scilit:
- Stereospecific Nicotine Receptors on Rat Brain MembranesScience, 1980
- Stereospecific 3H-nicotine binding to intact and solubilized rat brain membranes and evidence for its noncholinergic natureLife Sciences, 1980
- Acute and chronic effects of nicotine in rats and evidence for a noncholinergic site of action.1979
- EVIDENCE FOR A NONCHOLINERGIC SITE FOR NICOTINES ACTION IN BRAIN - PSYCHOPHARMACOLOGICAL, ELECTRO-PHYSIOLOGICAL AND RECEPTOR-BINDING STUDIES1979
- Electrophysiological, behavioral, and chemical evidence for a noncholinergic, stereospecific site for nicotine in rat brainJournal of Neuroscience Research, 1978
- Barrel rotation induced by vasopressin and related peptides in ratsPharmacology Biochemistry and Behavior, 1977