Hypnotic Effect of Thiopental–Lidocaine Combination in the Rat
Open Access
- 1 October 1982
- journal article
- research article
- Published by Wolters Kluwer Health in Anesthesiology
- Vol. 57 (4) , 311-313
- https://doi.org/10.1097/00000542-198210000-00013
Abstract
Isobolographic analysis was used to assess quantitatively the combined hypnotic effect of thiopental and lidocaine and to define the type of interaction between these 2 drugs. Combined administration of thiopental and lidocaine results in infra-additive interaction (relative antagonism).Keywords
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