Marked Decrease in Serum HDL Cholesterol Level during Acute Myocardial Infarction

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Abstract
The concentrations of serum total and HDL cholesterol and triglycerides were determined in 57 patients during the course of AMI. In seven days the concentration of serum cholesterol decreased by 24% and that of HDL cholesterol by 31%. The mean HDL/total cholesterol ratio decreased significantly (pr = –0.66) and after four months (r = –0.53) but no correlation after seven days. The results indicate that the determination of serum lipids, including HDL cholesterol, in patients with AMI can, and should be performed on admission to hospital and not at the time of discharge, in order to get reliable estimates of these cardiovascular risk factors.