Changing pattern of malaria in Bissau, Guinea Bissau
- 1 March 2008
- journal article
- research article
- Published by Wiley in Tropical Medicine & International Health
- Vol. 13 (3) , 410-417
- https://doi.org/10.1111/j.1365-3156.2008.02016.x
Abstract
To describe the epidemiology of malaria in Guinea-Bissau, in view of the fact that more funds are available now for malaria control in the country. From May 2003 to May 2004, surveillance for malaria was conducted among children less than 5 years of age at three health centres covering the study area of the Bandim Health Project (BHP) and at the outpatient clinic of the national hospital in Bissau. Cross-sectional surveys were conducted in the community in different malaria seasons. Malaria was overdiagnosed in both health centres and hospital. Sixty-four per cent of the children who presented at a health centre were clinically diagnosed with malaria, but only 13% of outpatient children who tested for malaria had malaria parasitaemia. Only 44% (963/2193) of children admitted to hospital with a diagnosis of malaria had parasitaemia. The proportion of positive cases increased with age. Among hospitalized children with malaria parasitaemia, those less than 2 years old were more likely to have moderate anaemia (RR = 1.27; 95% CI: 1.02-1.56) (P = 0.03) or severe anaemia (RR = 1.67; 95% CI: 1.25-2.24) (P = 0.0005) than older children. The prevalence of malaria parasitaemia in the community was low (3%, 53/1926). In Bissau, the prevalence of malaria parasitaemia in the community is now low and malaria is over-diagnosed in health facilities. Laboratory support will be essential to avoid unnecessary use of the artemisinin combination therapy which is now being introduced as first-line treatment in Bissau with support from the Global Fund.Keywords
This publication has 19 references indexed in Scilit:
- Improved Diagnostic Testing and Malaria Treatment Practices in ZambiaJAMA, 2007
- Treatment of malaria restricted to laboratory-confirmed cases: a prospective cohort study in Ugandan childrenMalaria Journal, 2007
- LABORATORY USE IN GHANA: PHYSICIAN PERCEPTION AND PRACTICEThe American Journal of Tropical Medicine and Hygiene, 2006
- Malaria misdiagnosis: effects on the poor and vulnerableThe Lancet, 2004
- No benefits from combining chloroquine with artesunate for three days for treatment of Plasmodium falciparum in Guinea-BissauTransactions of the Royal Society of Tropical Medicine and Hygiene, 2003
- Treatment of uncomplicated malaria in children in Guinea-Bissau with chloroquine, quinine, and sulfadoxine-pyrimethamineTransactions of the Royal Society of Tropical Medicine and Hygiene, 2002
- Do untreated bednets protect against malaria?Transactions of the Royal Society of Tropical Medicine and Hygiene, 2001
- Does the availability of blood slide microscopy for malaria at health centers improve the management of persons with fever in Zambia?The American Journal of Tropical Medicine and Hygiene, 1999
- A community study of T lymphocyte subsets and malaria parasitaemiaTransactions of the Royal Society of Tropical Medicine and Hygiene, 1994
- Control of endophagic Anopheles mosquitoes and human malaria in Guinea Bissau, West Africa by permethrin-treated bed netsTransactions of the Royal Society of Tropical Medicine and Hygiene, 1994