Absorption of Recombinant Human Granulocyte Colony-Stimulating Factor (rhG-CSF) from Rat Nasal Mucosa
- 1 January 1993
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 10 (9) , 1372-1377
- https://doi.org/10.1023/a:1018990318090
Abstract
Nasal absorption of recombinant human granulocyte colony-stimulating factor (rhG-CSF) was examined in the rat. The relative bioavailability of rhG-CSF for subcutaneous administration was ∼2%, as...Keywords
This publication has 7 references indexed in Scilit:
- The Molecular Weight Dependence of Nasal Absorption: The Effect of Absorption EnhancersPharmaceutical Research, 1990
- Protective activity of recombinant cytokines against Sendai virus and herpes simplex virus (HSV) infections in miceVaccine, 1989
- Quantitative enzyme immunoassay for human granulocyte colony stimulating factor (G-CSF)Journal of Immunological Methods, 1989
- Structures of the Sugar Chains of Recombinant Human Granulocyte-Colony-Stimulating Factor Produced by Chinese Hamster Ovary CellsThe Journal of Biochemistry, 1988
- Analysis of Structural Requirements for the Absorption of Drugs and Macromolecules from the Nasal CavityJournal of Pharmaceutical Sciences, 1987
- Intranasal drug delivery for systemic medications.1987
- Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factorNature, 1986