The Stunting of Growth in Young Rabbits Injected with Strontium 90
- 1 January 1961
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Vol. 3 (5) , 515-523
- https://doi.org/10.1080/09553006114550691
Abstract
The effect of an injection of 90Sr on the growth of young rabbits was studied. Two levels of injection were used, 100[mu]c of 90sr per kilogram of body-weight, and 600 [mu]c/kg. The animals were killed at various time-intervals after injection, up to 180 days later. Measurements were made on the terminal body-weight, weight of the femur and tibia, and length of the tibia, both for injected animals and controls. All the four measurements on the animals which received 600 [mu]c/kg showed significant stunting of growth, while the animals injected with 100 )[mu]c/kg were not significantly different from the controls. The growth of the proximal epiphyseal cartilage plate of the tibia, during the first few weeks after injection, was also measured radiographically: the animals with 600 [mu]c/kg again showed significant stunting of growth. Some observations on the radiation dosimetry and pathology of the animals are discussed briefly.Keywords
This publication has 4 references indexed in Scilit:
- Radiation Dose and its Relation to Damage in the Rabbit Tibia Following a Single Injection and Daily Feeding of 90SrBritish Journal of Cancer, 1959
- A Comparison of Bone Growth in Normal and Strontium-Treated RatsJournal of Dental Research, 1959
- The Effect of a Single Injection of High Dose of 90Sr (500-1000 μc./Kg.) in RabbitsBritish Journal of Cancer, 1957
- AN ANALYSIS OF CERTAIN CHEMICAL CONSTITUENTS OF RABBIT BONE FOLLOWING DEPOSITION OF SR-901956