The Effects of Inbreeding and of Some Genetic Polymorphisms on Blood Pressures, Pulse Rate and Hematocrit in Northeastern Brazil
- 31 December 1978
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 29 (2) , 106-110
- https://doi.org/10.1159/000153025
Abstract
The possible role of genetic mechanisms [as revealed by inbreeding depression and pleiotropic effects of the ABO, Es D[esterase D] and CA II [cavbonic anhydrase II] loci] on blood pressures, pulse rate and hematocrit was studied in a sample of 7642 migrant Brazilian individuals of rural origin. It was not possible to confirm previous claims of the effects of ABO blood groups system and inbreeding on diastolic blood pressure. A significant inbreeding depression on pulse rate of about 1.23 bpm(beats per minute)/10% F, among adult individuals, was revealed. The observed significant effects of several markers on hemodynamic variables, due to its number, were attributed to chance.This publication has 4 references indexed in Scilit:
- FAMILIAL STUDIES OF MEDICAL AND ANTHROPOMETRIC VARIABLES IN A HUMAN ISOLATE1973
- Racial admixture in north‐eastern BrazilAnnals of Human Genetics, 1965
- HUMAN BLOOD PRESSURE AND ABO BLOOD GROUP SYSTEM - AN APPARENT ASSOCIATION1965
- Blood Pressure Correlation Between Relatives in an Endogamic PopulationHuman Heredity, 1965