Differentiation of Extramedullary Acute Promyelocytic Leukemia by All-Trans-Retinoic Acid
- 1 January 1995
- journal article
- case report
- Published by Taylor & Francis in Leukemia & Lymphoma
- Vol. 18 (1-2) , 189-193
- https://doi.org/10.3109/10428199509064942
Abstract
The effect of all-trans-retinoic acid (ATRA) on extramedullary acute promyelocytic leukemia (APL) has not been fully delineated. We report an unusual case of APL in which a patient relapsed in the skin and central nervous system. Cytodifferentiation of leukemic cells from these extramedullary sites was demonstrated following treatment with ATRA.Keywords
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