Cispentacin, A new antifungal antibiotic I. Production, isolation, physico-chemical properties and structure.
- 1 January 1989
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 42 (12) , 1749-1755
- https://doi.org/10.7164/antibiotics.42.1749
Abstract
A new antibiotic, cispentacin, was isolated from the culture broth of a Bacillus cereus strain, L450-B2. The antibiotic is water-soluble and amphoteric; its structure was determined by spectroscopic analysis and chemical synthesis to be (1R,2S)-2-aminocyclopentane-1-carboxylic acid. Cispentacin demonstrated only weak in vitro activity against certain fungi but strong protection of mice from lethal infection of candida albicans A9540.This publication has 2 references indexed in Scilit:
- Cispentacin, a new antifungal antibiotic. II. In vitro and in vivo antifungal activities.The Journal of Antibiotics, 1989
- Contribution to the Characterization of Bacillus megateriumInternational Journal of Systematic and Evolutionary Microbiology, 1979