An Assessment of Gastric Acid Secretory Response with `Maximal' Augmented Histamine Stimulation in Children with Peptic Ulcer

Open Access
Publisher Website
Google Scholar
Abstract
The results of the "maximal" augmented histamine test on 18 radiologically proven cases of duodenal ulcer in children and 16 control subjects are presented. All received triple sedative injection half an hour before the start of the test. The mean basal and the maximal acid output in control subjects were 0. 32 mEq/10 kg. hour and 2. 02 mEq/10 kg. hour, respectively. There was a singificant correlation between body weight and "maximal" acid output in control subjects. There was no significant difference between basal outputs in duodenal ulcer patients and control subjects. Eleven patients with duodenal ulcer (61%) secreted "maximal" acid in amounts more than 2. 50 mEq/10 kg. hour while only 3 control children (19%) did so. A direct correlation between the activity of the ulcer and maximal acid output was observed.

This publication has 20 references indexed in Scilit: