INSULIN-INSENSITIVITY: ITS POSSIBLE RELATION TO THE PITUITARY GLAND1
- 1 November 1938
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 23 (5) , 630-636
- https://doi.org/10.1210/endo-23-5-630
Abstract
8 patients (3 normal, 3 with diabetes mellitus who were clinically "insulin-sensitive," and 2 with acromegaly and diabetes mellitus who demonstrated "insu-lin-insensitivity") were studied by means of the glucose tolerance and simultaneous glucose-and-insulin blood-sugar curves. The "insulin-sensitive" diabetics resembled normal individuals in showing a suppression of the postglucose hyperglycemia in the glucose-and-insulin curves. In 2 patients with acromegaly and diabetes the simultaneous intraven. inj. of insulin had little effect in suppressing the postglucose hyperglycemia. The tumor of the pituitary gland demonstrated in these patients is an etiologic factor in the "insulin-insensitivity.".This publication has 1 reference indexed in Scilit:
- RESPONSE TO INSULIN AS AN INDEX TO THE DIETARY MANAGEMENT OF DIABETESJournal of Clinical Investigation, 1936