On the mechanism of energy transduction in myosin subfragment 1.

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Abstract
It is proposed that the [rabbit] myosin subfragment 1 moiety of the muscle contractile apparatus is a self-contained engine, the operational plan of which is based on the interactive nature of ATP (or degradation intermediate) binding and actin binding, make possible by an intersite communication system. Evidently, the spatial information required for examining this engine can, at least provisionally, be derived from fluorescence resonance energy transfer measurements interpreted by the Foerster equation and the existence of an intersite communication system can be deduced from piece-wise detection of interactig pairs of points.