Cell Interaction During Lymphocyte Activation
- 1 January 1978
- journal article
- research article
- Published by Taylor & Francis in Immunological Communications
- Vol. 7 (3) , 251-260
- https://doi.org/10.3109/08820137809025470
Abstract
Adherent cells were separated from stimulated lymphocytes by a layer of agarose to determine the requirement for lynphocyte interaction with adherent cells. The results demonstrated that the presence of plastic adherent cells was obligatory for oxidative activation, but contact of plastic adherent cells with oxidized nonadherent lymphocytes was not. A similar relationship was found to exist between adherent and nonadherent populations during PHA and Con A stimulation. In contrast, the responses of PWM- and ZnC12-stimulated lymphocytes were not augmented by the presence of adherent cells unless the two populations were in contact.This publication has 4 references indexed in Scilit:
- Sodium periodate stimulation of human lymphocytes: A comparison between normal and chronic lymphocytic leukemia lymphocytesExperimental Cell Research, 1975