Antimicrobial activity and other in vitro properties of cefoperazone A, the principal metabolite of cefoperazone sodium
- 1 August 1983
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 24 (2) , 293-296
- https://doi.org/10.1128/aac.24.2.293
Abstract
Cefoperazone A, the principal metabolite of cefoperazone, was found to have an antimicrobial activity ranging from slightly below to 16-fold less than that of the parent drug. Like cefoperazone, the metabolite is bactericidal, penetrates well into bacterial cells, and has moderate beta-lactamase stability, some strains of members of the family Enterobacteriaceae produce an inoculum effect on the metabolite activity.Keywords
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