Inactivation of Enzyme-Substrate Films by Small Doses of X-Rays
- 1 July 1948
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 34 (7) , 328-336
- https://doi.org/10.1073/pnas.34.7.328
Abstract
Pepsin-albumin films were inactivated by small doses of x-rays. Doses of about 100 r produced about 50% inactivation. The sensitivity to radiation depended on the physical configuration of the molecules. It was varied by surface compression. Calculations suggested that the effects of a single radiation event (ionization or radiacal production) may have spread to include a large number to enzyme molecules.Keywords
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