On some statistical methods for analysis of combination drug studies∗
- 1 January 1994
- journal article
- research article
- Published by Taylor & Francis in Communications in Statistics - Theory and Methods
- Vol. 23 (2) , 361-376
- https://doi.org/10.1080/03610929408831260
Abstract
To be discussed are the practical considerations in the use of some statistical methods to evaluate clinical data for combination antihypertensive agents. The issues of interest concern efficacy and dose-response in a factorial clinical trial for multiple dose combinations. Discussions cover fixed-dose combination studies.Keywords
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