The role of antiepileptics in sudden death in epilepsy
- 1 October 1985
- journal article
- research article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 72 (4) , 444-446
- https://doi.org/10.1111/j.1600-0404.1985.tb00898.x
Abstract
– In a material of sudden, unexpected death of epileptic patients treated with one or more of the anticonvulsants phenobarbitone, phenytoin and car-bamazepine we found subtherapeutic drug levels in half of the cases and lethal concentrations, mainly of phenobarbitone, in one third of the cases. The results illustrate the severe consequences of noncompliance in epilepsy, and stress the value of blood drug level control.Keywords
This publication has 3 references indexed in Scilit:
- Practical aspects in the treatment of epilepsyActa Neurologica Scandinavica, 1983
- Self-Poisoning — A Complication of EpilepsyThe British Journal of Psychiatry, 1979
- Premature Deaths in Persons with Seizure Disorders—Subtherapeutic Levels of Anticonvulsant Drugs in Postmortem Blood SpecimensJournal of Forensic Sciences, 1978