Specificity in pleckstrin homology (PH) domain membrane targeting: a role for a phosphoinositide–protein co‐operative mechanism
Open Access
- 23 September 2001
- journal article
- review article
- Published by Wiley in FEBS Letters
- Vol. 506 (3) , 173-179
- https://doi.org/10.1016/s0014-5793(01)02909-x
Abstract
Pleckstrin homology (PH) domains are protein modules found in proteins involved in many cellular processes. The majority of PH domain‐containing proteins require membrane association for their functi...Keywords
This publication has 50 references indexed in Scilit:
- Modulation of Oncogenic DBL Activity by Phosphoinositol Phosphate Binding to Pleckstrin Homology DomainJournal of Biological Chemistry, 2001
- Interaction between the Btk PH Domain and Phosphatidylinositol-3,4,5-trisphosphate Directly Regulates BtkJournal of Biological Chemistry, 2001
- Cloning and Characterization of PHIP, a Novel Insulin Receptor Substrate-1 Pleckstrin Homology DomainInteracting ProteinJournal of Biological Chemistry, 2000
- Distinct Polyphosphoinositide Binding Selectivities for Pleckstrin Homology Domains of GRP1-like Proteins Based on DiglycineVersus Triglycine MotifsJournal of Biological Chemistry, 2000
- The Role of the Pleckstrin Homology Domain in Membrane Targeting and Activation of Phospholipase Cβ1Journal of Biological Chemistry, 2000
- PLECKSTRIN HOMOLOGY DOMAINS: A Common Fold with Diverse FunctionsAnnual Review of Biophysics, 1998
- Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesisNature, 1996
- The Pleckstrin Homology Domain Is the Principle Link between the Insulin Receptor and IRS-1Journal of Biological Chemistry, 1996
- Binding of Pleckstrin Homology Domains to WD40/β-Transducin Repeat Containing Segments of the Protein Product of the Lis-1 GeneBiochemical and Biophysical Research Communications, 1995
- Binding of PH Domains of β-Adrenergic-Receptor Kinase and β-Spectrin to WD40/β-Transducin Repeat Containing Regions of the β-Subunit of Trimeric G-ProteinsBiochemical and Biophysical Research Communications, 1994