Predictors of risk of intracerebral haemorrhage in patients with a history of TIA or minor ischaemic stroke
Open Access
- 1 January 2006
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 77 (1) , 92-94
- https://doi.org/10.1136/jnnp.2004.059923
Abstract
We developed a model identifying patients with previous cerebral ischaemia at increased risk of intracerebral haemorrhage (ICH). Based on data from eight cohorts, 107 ICHs were found to have occurred among 12 648 patients. Multivariate Cox regression analysis identified the following predictors: age (⩾60 years, hazard ratio (HR) 2.07), blood glucose level (⩾7 mmol/l, HR 0.33), systolic blood pressure (⩾140 mm Hg, HR 2.17), and antihypertensive drugs (HR 1.53). The highest risk quartile was associated with five times more ICHs than the lowest quartile.Keywords
This publication has 8 references indexed in Scilit:
- Regression dilution of systolic and diastolic blood pressure in patients with established cerebrovascular diseaseJournal of Clinical Epidemiology, 2003
- Risk Factors for Intracerebral Hemorrhage in the General PopulationStroke, 2003
- Long-Term Outcome after Ischaemic Stroke/Transient Ischaemic AttackCerebrovascular Diseases, 2003
- A randomized trial of anticoagulants versus aspirin after cerebral ischemia of presumed arterial originAnnals of Neurology, 1997
- Comparable Studies of the Incidence of Stroke and its Pathological TypesStroke, 1997
- Spectrum of primary intracerebral haemorrhage in Perth, Western Australia, 1989-90: incidence and outcome.Journal of Neurology, Neurosurgery & Psychiatry, 1994
- A Comparison of Two Doses of Aspirin (30 mg vs. 283 mg a Day) in Patients after a Transient Ischemic Attack or Minor Ischemic StrokeNew England Journal of Medicine, 1991
- A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project--1981-86. 2. Incidence, case fatality rates and overall outcome at one year of cerebral infarction, primary intracerebral and subarachnoid haemorrhage.Journal of Neurology, Neurosurgery & Psychiatry, 1990