A melanin‐dispersing effect of cyclic adenosine monophosphate on Fundulus melanophores
Open Access
- 1 February 1970
- journal article
- research article
- Published by Wiley in Journal of Cellular Physiology
- Vol. 75 (1) , 133-135
- https://doi.org/10.1002/jcp.1040750116
Abstract
Treatment of Fundulus melanophores with adenosine 3′,5′‐monophosphate (cyclic AMP) is followed by reversible melanin dispersion in these cells. Adenosine 3′‐monophosphate and adenosine 5′‐monophosphate both have a similar, but weaker dispersing action. In addition, adenosine 5′‐monophosphate also has a melanin aggregating effect. These results are interpreted to mean that nerve transmitters may act by controlling the level of cyclic AMP within the Fundulus melanophore.Keywords
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