The metabolism of lindane and its metabolites gamma‐2, 3, 4, 5, 6‐pentachlorocyclohexene, pentachlorobenzene, and pentachlorophenol in rats and the pathways of lindane metabolism
- 1 January 1976
- journal article
- Published by Taylor & Francis in Journal of Environmental Science and Health, Part B
- Vol. 11 (2) , 95-117
- https://doi.org/10.1080/03601237609372028
Abstract
The metabolism of lindane and its metabolites, gamma-PCCH, PCB, and PCP, has been studied in rats. Urine, faeces, blood and important organs were analyzed for free metabolities and those bound as beta-glucuronides. TeCCOL was identified as a main metabolite by GC/MS and gamma-PCCH has been evaluated toxicologically. A degradation scheme, based on experimental results and comprising only one hypothetical metabolite is proposed and discussed.Keywords
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