Pantothenate-requiring dwarf colony variants ofStaphylococcus aureusas the etiological agent in bovine mastitis

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Abstract
In a herd affected with bovine mastitis, dwarf colony variants ofStaphylococcus aureus, auxotrophic for Ca-pantothenate, were isolated from the milk of four cows with mastitis. From one of these cows, a dwarf variant with an unknown metabolic disorder was isolated during the same period. Infections with auxo trophic staphylococci were always chronic and proved to be refractory to anti biotic treatment, though the causative micro-organism was highly susceptible to the drugs used as judged byin vitrotests.The authors acknowledge with appreciation the skilful help of Miss Nili Abramova.